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Detroit Mayor Duggan doubles down on not wanting J&J vaccine for foreseeable future – Crains Detroit Business

The city of Detroit declined its alloted Johnson & Johnson COVID-19 vaccine doses this week, and Mayor Mike Duggan doubled down Thursday on his reasoning for sticking with the vaccines from Moderna and Pfizer.

“Johnson & Johnson is a very good vaccine. Moderna and Pfizer are the best,” Duggan said in a news conference. “And I am going to do everything I can to make sure that residents of the city of Detroit get the best.”

Detroit would have received 6,200 of the J&J one-shot doses, but declined to do so and did not get more Moderna and Pfizer doses to make up for it, according to Bob Wheaton, public information officer in the Michigan Department of Health and Human Services. They went to “other health departments that had lower coverage rates for those age 65 years or older,” Wheaton wrote in an email.

Detroit got 17,000 first Moderna and Pfizer doses and 12,000 second doses this week for a total of 29,000. That’s up from 15,000 a week at the start of February. Duggan expects to get 25,000-30,000 more next week.

“I believe we will have a Moderna and Pfizer vaccine for every Detroiter who wants one. The day may come when we have more Detroiters asking for vaccines than we have Moderna, Pfizer, in which case we’ll set up a Johnson & Johnson site … I don’t see that in the next couple weeks,” he said. “I’d say for the foreseeable future, I feel confident that we will have a Moderna and Pfizer vaccine for everyone who wants to get vaccinated.”

The Detroit Free Press first reported that Detroit had rejected J&J doses.

Compared with the two-dose versions produced by Moderna and Pfizer, the J&J vaccine is less resource-intensive to distribute and administer. It can be stored for months at refrigerated temperatures, rather than frozen, and doesn’t require patients to return for a second dose three or four weeks later. That is a positive sign to officials who expect to accelerate vaccine administration across the country.

However, Duggan said the city’s vaccine administration system runs smoothly handling two types of two-dose vaccines in one big site at the TCF Center garage downtown. He added that he thinks it’s “worth it” for the added protection to do the extra work.

Food and Drug Administration scientists confirmed that overall the J&J vaccine is about 66 percent effective at preventing moderate to severe COVID-19, and about 85 percent effective against the most serious illness. The agency also said J&J’s vaccine is safe. The other two are 95 percent effective against symptomatic COVID-19.

“CDC has recommended its use for all adults age 18 or over,” MDHHS spokesman Wheaton wrote in an email. “All immunizing providers who can manage vaccine storage and management for a vaccine are expected to accept vaccine.

“The Johnson and Johnson vaccines were distributed to local health departments and some hospitals this week so that all doses were allocated on top of the Moderna and Pfizer distribution. The city of Detroit allocation of Johnson and Johnson vaccine was 6,200. They did not receive additional Moderna or Pfizer vaccine to replace the Johnson and Johnson vaccine.”
Francis Collins, director of the National Institutes of Health, told the Associated Press that evidence shows no reason to favor one vaccine over another.

“What people I think are mostly interested in is, is it going to keep me from getting really sick?” Collins told the AP. “Will it keep me from dying from this terrible disease? The good news is all of these say yes to that.”

Detroit has gotten national recognition for its efficiency testing and vaccinating residents through mass sites.

However, the city still lags surrounding counties and the state as a whole when it comes to total percent of adults immunized. Of Detroit adults, 11 percent have been vaccinated so far. For Macomb County, the figure is 16.5 percent; 19.1 percent for Oakland County; 18.6 percent for outer Wayne County, and 18.5 percent for Michigan as a whole.

Nearly 251,000 vaccines have been distributed in Detroit as of Wednesday, with nearly 130,000 of those going to the city government, according to state and local data. Others go to private providers, including heath care systems.

The federal government announced this week that it was increasing supply of the Moderna and Pfizer vaccines to states next week to 15.2 million doses per week, up from 14.5 million previously. States were also to receive 2.8 million doses of the J&J shot this week.

New Thursday, the TCF Center garage vaccination site is now allowing any Detroit resident with underlying conditions ages 50 and older to schedule appointments by calling (313) 230-0505. Other eligible groups include food, manufacturing and health care workers. More details are on the city’s website.

Duggan said Thursday he believes is Detroit is the only city in the U.S. in which grocery workers and those in manufacturing who live and/or work in the city can be vaccinated.

The state on Wednesday announced it is expanding eligibility to people 50 years old and up with disabilities or pre-existing medical conditions and caregivers of children with special health care needs starting March 8. Detroit is doing the same.

On March 22, any Michigan resident age 50 and older will be able to get one of the three vaccines available, Whitmer spokesman Bobby Leddy said.

Detroit also marked a milestone Thursday, administering its 100,000th vaccine dose. Around two-thirds of those have gone to Detroiters and the other third to non-Detroiters who work in the city, Duggan estimated Thursday.
The drive-through site has gone from a couple hundred then 1,000 appointments a day to 4,500 Thursday. The most it can handle is 5,000.

— The Associated Press contributed to this report.

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Detroit Mayor Duggan doubles down on not wanting J&J vaccine for foreseeable future – Crains Detroit Business

The city of Detroit declined its alloted Johnson & Johnson COVID-19 vaccine doses this week, and Mayor Mike Duggan doubled down Thursday on his reasoning for sticking with the vaccines from Moderna and Pfizer.

“Johnson & Johnson is a very good vaccine. Moderna and Pfizer are the best,” Duggan said in a news conference. “And I am going to do everything I can to make sure that residents of the city of Detroit get the best.”

Detroit would have received 6,200 of the J&J one-shot doses, but declined to do so and did not get more Moderna and Pfizer doses to make up for it, according to Bob Wheaton, public information officer in the Michigan Department of Health and Human Services. They went to “other health departments that had lower coverage rates for those age 65 years or older,” Wheaton wrote in an email.

Detroit got 17,000 first Moderna and Pfizer doses and 12,000 second doses this week for a total of 29,000. That’s up from 15,000 a week at the start of February. Duggan expects to get 25,000-30,000 more next week.

“I believe we will have a Moderna and Pfizer vaccine for every Detroiter who wants one. The day may come when we have more Detroiters asking for vaccines than we have Moderna, Pfizer, in which case we’ll set up a Johnson & Johnson site … I don’t see that in the next couple weeks,” he said. “I’d say for the foreseeable future, I feel confident that we will have a Moderna and Pfizer vaccine for everyone who wants to get vaccinated.”

The Detroit Free Press first reported that Detroit had rejected J&J doses.

Compared with the two-dose versions produced by Moderna and Pfizer, the J&J vaccine is less resource-intensive to distribute and administer. It can be stored for months at refrigerated temperatures, rather than frozen, and doesn’t require patients to return for a second dose three or four weeks later. That is a positive sign to officials who expect to accelerate vaccine administration across the country.

However, Duggan said the city’s vaccine administration system runs smoothly handling two types of two-dose vaccines in one big site at the TCF Center garage downtown. He added that he thinks it’s “worth it” for the added protection to do the extra work.

Food and Drug Administration scientists confirmed that overall the J&J vaccine is about 66 percent effective at preventing moderate to severe COVID-19, and about 85 percent effective against the most serious illness. The agency also said J&J’s vaccine is safe. The other two are 95 percent effective against symptomatic COVID-19.

“CDC has recommended its use for all adults age 18 or over,” MDHHS spokesman Wheaton wrote in an email. “All immunizing providers who can manage vaccine storage and management for a vaccine are expected to accept vaccine.

“The Johnson and Johnson vaccines were distributed to local health departments and some hospitals this week so that all doses were allocated on top of the Moderna and Pfizer distribution. The city of Detroit allocation of Johnson and Johnson vaccine was 6,200. They did not receive additional Moderna or Pfizer vaccine to replace the Johnson and Johnson vaccine.”
Francis Collins, director of the National Institutes of Health, told the Associated Press that evidence shows no reason to favor one vaccine over another.

“What people I think are mostly interested in is, is it going to keep me from getting really sick?” Collins told the AP. “Will it keep me from dying from this terrible disease? The good news is all of these say yes to that.”

Detroit has gotten national recognition for its efficiency testing and vaccinating residents through mass sites.

However, the city still lags surrounding counties and the state as a whole when it comes to total percent of adults immunized. Of Detroit adults, 11 percent have been vaccinated so far. For Macomb County, the figure is 16.5 percent; 19.1 percent for Oakland County; 18.6 percent for outer Wayne County, and 18.5 percent for Michigan as a whole.

Nearly 251,000 vaccines have been distributed in Detroit as of Wednesday, with nearly 130,000 of those going to the city government, according to state and local data. Others go to private providers, including heath care systems.

The federal government announced this week that it was increasing supply of the Moderna and Pfizer vaccines to states next week to 15.2 million doses per week, up from 14.5 million previously. States were also to receive 2.8 million doses of the J&J shot this week.

New Thursday, the TCF Center garage vaccination site is now allowing any Detroit resident with underlying conditions ages 50 and older to schedule appointments by calling (313) 230-0505. Other eligible groups include food, manufacturing and health care workers. More details are on the city’s website.

Duggan said Thursday he believes is Detroit is the only city in the U.S. in which grocery workers and those in manufacturing who live and/or work in the city can be vaccinated.

The state on Wednesday announced it is expanding eligibility to people 50 years old and up with disabilities or pre-existing medical conditions and caregivers of children with special health care needs starting March 8. Detroit is doing the same.

On March 22, any Michigan resident age 50 and older will be able to get one of the three vaccines available, Whitmer spokesman Bobby Leddy said.

Detroit also marked a milestone Thursday, administering its 100,000th vaccine dose. Around two-thirds of those have gone to Detroiters and the other third to non-Detroiters who work in the city, Duggan estimated Thursday.
The drive-through site has gone from a couple hundred then 1,000 appointments a day to 4,500 Thursday. The most it can handle is 5,000.

— The Associated Press contributed to this report.

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Detroit Mayor Duggan doubles down on not wanting J&J vaccine for foreseeable future – Crains Detroit Business

The city of Detroit declined its alloted Johnson & Johnson COVID-19 vaccine doses this week, and Mayor Mike Duggan doubled down Thursday on his reasoning for sticking with the vaccines from Moderna and Pfizer.

“Johnson & Johnson is a very good vaccine. Moderna and Pfizer are the best,” Duggan said in a news conference. “And I am going to do everything I can to make sure that residents of the city of Detroit get the best.”

Detroit would have received 6,200 of the J&J one-shot doses, but declined to do so and did not get more Moderna and Pfizer doses to make up for it, according to Bob Wheaton, public information officer in the Michigan Department of Health and Human Services. They went to “other health departments that had lower coverage rates for those age 65 years or older,” Wheaton wrote in an email.

Detroit got 17,000 first Moderna and Pfizer doses and 12,000 second doses this week for a total of 29,000. That’s up from 15,000 a week at the start of February. Duggan expects to get 25,000-30,000 more next week.

“I believe we will have a Moderna and Pfizer vaccine for every Detroiter who wants one. The day may come when we have more Detroiters asking for vaccines than we have Moderna, Pfizer, in which case we’ll set up a Johnson & Johnson site … I don’t see that in the next couple weeks,” he said. “I’d say for the foreseeable future, I feel confident that we will have a Moderna and Pfizer vaccine for everyone who wants to get vaccinated.”

The Detroit Free Press first reported that Detroit had rejected J&J doses.

Compared with the two-dose versions produced by Moderna and Pfizer, the J&J vaccine is less resource-intensive to distribute and administer. It can be stored for months at refrigerated temperatures, rather than frozen, and doesn’t require patients to return for a second dose three or four weeks later. That is a positive sign to officials who expect to accelerate vaccine administration across the country.

However, Duggan said the city’s vaccine administration system runs smoothly handling two types of two-dose vaccines in one big site at the TCF Center garage downtown. He added that he thinks it’s “worth it” for the added protection to do the extra work.

Food and Drug Administration scientists confirmed that overall the J&J vaccine is about 66 percent effective at preventing moderate to severe COVID-19, and about 85 percent effective against the most serious illness. The agency also said J&J’s vaccine is safe. The other two are 95 percent effective against symptomatic COVID-19.

“CDC has recommended its use for all adults age 18 or over,” MDHHS spokesman Wheaton wrote in an email. “All immunizing providers who can manage vaccine storage and management for a vaccine are expected to accept vaccine.

“The Johnson and Johnson vaccines were distributed to local health departments and some hospitals this week so that all doses were allocated on top of the Moderna and Pfizer distribution. The city of Detroit allocation of Johnson and Johnson vaccine was 6,200. They did not receive additional Moderna or Pfizer vaccine to replace the Johnson and Johnson vaccine.”
Francis Collins, director of the National Institutes of Health, told the Associated Press that evidence shows no reason to favor one vaccine over another.

“What people I think are mostly interested in is, is it going to keep me from getting really sick?” Collins told the AP. “Will it keep me from dying from this terrible disease? The good news is all of these say yes to that.”

Detroit has gotten national recognition for its efficiency testing and vaccinating residents through mass sites.

However, the city still lags surrounding counties and the state as a whole when it comes to total percent of adults immunized. Of Detroit adults, 11 percent have been vaccinated so far. For Macomb County, the figure is 16.5 percent; 19.1 percent for Oakland County; 18.6 percent for outer Wayne County, and 18.5 percent for Michigan as a whole.

Nearly 251,000 vaccines have been distributed in Detroit as of Wednesday, with nearly 130,000 of those going to the city government, according to state and local data. Others go to private providers, including heath care systems.

The federal government announced this week that it was increasing supply of the Moderna and Pfizer vaccines to states next week to 15.2 million doses per week, up from 14.5 million previously. States were also to receive 2.8 million doses of the J&J shot this week.

New Thursday, the TCF Center garage vaccination site is now allowing any Detroit resident with underlying conditions ages 50 and older to schedule appointments by calling (313) 230-0505. Other eligible groups include food, manufacturing and health care workers. More details are on the city’s website.

Duggan said Thursday he believes is Detroit is the only city in the U.S. in which grocery workers and those in manufacturing who live and/or work in the city can be vaccinated.

The state on Wednesday announced it is expanding eligibility to people 50 years old and up with disabilities or pre-existing medical conditions and caregivers of children with special health care needs starting March 8. Detroit is doing the same.

On March 22, any Michigan resident age 50 and older will be able to get one of the three vaccines available, Whitmer spokesman Bobby Leddy said.

Detroit also marked a milestone Thursday, administering its 100,000th vaccine dose. Around two-thirds of those have gone to Detroiters and the other third to non-Detroiters who work in the city, Duggan estimated Thursday.
The drive-through site has gone from a couple hundred then 1,000 appointments a day to 4,500 Thursday. The most it can handle is 5,000.

— The Associated Press contributed to this report.

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TDH reports 103 new COVID-19 cases, 4 new deaths in NETN on Thursday – WJHL-TV News Channel 11

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School employees of all ages able to receive COVID-19 vaccine at Orlando FEMA vaccination site – WFTV Orlando

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Detroit Mayor Duggan doubles down on not wanting J&J vaccine for foreseeable future – Crains Detroit Business

The city of Detroit declined its alloted Johnson & Johnson COVID-19 vaccine doses this week, and Mayor Mike Duggan doubled down Thursday on his reasoning for sticking with the vaccines from Moderna and Pfizer.

“Johnson & Johnson is a very good vaccine. Moderna and Pfizer are the best,” Duggan said in a news conference. “And I am going to do everything I can to make sure that residents of the city of Detroit get the best.”

Detroit would have received 6,200 of the J&J one-shot doses, but declined to do so and did not get more Moderna and Pfizer doses to make up for it, according to Bob Wheaton, public information officer in the Michigan Department of Health and Human Services. They went to “other health departments that had lower coverage rates for those age 65 years or older,” Wheaton wrote in an email.

Detroit got 17,000 first Moderna and Pfizer doses and 12,000 second doses this week for a total of 29,000. That’s up from 15,000 a week at the start of February. Duggan expects to get 25,000-30,000 more next week.

“I believe we will have a Moderna and Pfizer vaccine for every Detroiter who wants one. The day may come when we have more Detroiters asking for vaccines than we have Moderna, Pfizer, in which case we’ll set up a Johnson & Johnson site … I don’t see that in the next couple weeks,” he said. “I’d say for the foreseeable future, I feel confident that we will have a Moderna and Pfizer vaccine for everyone who wants to get vaccinated.”

The Detroit Free Press first reported that Detroit had rejected J&J doses.

Compared with the two-dose versions produced by Moderna and Pfizer, the J&J vaccine is less resource-intensive to distribute and administer. It can be stored for months at refrigerated temperatures, rather than frozen, and doesn’t require patients to return for a second dose three or four weeks later. That is a positive sign to officials who expect to accelerate vaccine administration across the country.

However, Duggan said the city’s vaccine administration system runs smoothly handling two types of two-dose vaccines in one big site at the TCF Center garage downtown. He added that he thinks it’s “worth it” for the added protection to do the extra work.

Food and Drug Administration scientists confirmed that overall the J&J vaccine is about 66 percent effective at preventing moderate to severe COVID-19, and about 85 percent effective against the most serious illness. The agency also said J&J’s vaccine is safe. The other two are 95 percent effective against symptomatic COVID-19.

“CDC has recommended its use for all adults age 18 or over,” MDHHS spokesman Wheaton wrote in an email. “All immunizing providers who can manage vaccine storage and management for a vaccine are expected to accept vaccine.

“The Johnson and Johnson vaccines were distributed to local health departments and some hospitals this week so that all doses were allocated on top of the Moderna and Pfizer distribution. The city of Detroit allocation of Johnson and Johnson vaccine was 6,200. They did not receive additional Moderna or Pfizer vaccine to replace the Johnson and Johnson vaccine.”
Francis Collins, director of the National Institutes of Health, told the Associated Press that evidence shows no reason to favor one vaccine over another.

“What people I think are mostly interested in is, is it going to keep me from getting really sick?” Collins told the AP. “Will it keep me from dying from this terrible disease? The good news is all of these say yes to that.”

Detroit has gotten national recognition for its efficiency testing and vaccinating residents through mass sites.

However, the city still lags surrounding counties and the state as a whole when it comes to total percent of adults immunized. Of Detroit adults, 11 percent have been vaccinated so far. For Macomb County, the figure is 16.5 percent; 19.1 percent for Oakland County; 18.6 percent for outer Wayne County, and 18.5 percent for Michigan as a whole.

Nearly 251,000 vaccines have been distributed in Detroit as of Wednesday, with nearly 130,000 of those going to the city government, according to state and local data. Others go to private providers, including heath care systems.

The federal government announced this week that it was increasing supply of the Moderna and Pfizer vaccines to states next week to 15.2 million doses per week, up from 14.5 million previously. States were also to receive 2.8 million doses of the J&J shot this week.

New Thursday, the TCF Center garage vaccination site is now allowing any Detroit resident with underlying conditions ages 50 and older to schedule appointments by calling (313) 230-0505. Other eligible groups include food, manufacturing and health care workers. More details are on the city’s website.

Duggan said Thursday he believes is Detroit is the only city in the U.S. in which grocery workers and those in manufacturing who live and/or work in the city can be vaccinated.

The state on Wednesday announced it is expanding eligibility to people 50 years old and up with disabilities or pre-existing medical conditions and caregivers of children with special health care needs starting March 8. Detroit is doing the same.

On March 22, any Michigan resident age 50 and older will be able to get one of the three vaccines available, Whitmer spokesman Bobby Leddy said.

Detroit also marked a milestone Thursday, administering its 100,000th vaccine dose. Around two-thirds of those have gone to Detroiters and the other third to non-Detroiters who work in the city, Duggan estimated Thursday.
The drive-through site has gone from a couple hundred then 1,000 appointments a day to 4,500 Thursday. The most it can handle is 5,000.

— The Associated Press contributed to this report.

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CDC offers zombie preparedness tips in case Nostradamus is right – New York Post

French philosopher and prophet Michel de Nostradamus reportedly predicted a zombie apocalypse for 2021. 

But fear not!

The Centers for Disease Control and Prevention has your back with a set of zombie preparedness tips it has maintained for a full decade.

“Wonder why zombies, zombie apocalypse, and zombie preparedness continue to live or walk dead on a CDC web site?” asks the guide, which was developed in 2011 as a marketing gimmick — and an attention-grabbing one at that.

“As it turns out what first began as a tongue-in-cheek campaign to engage new audiences with preparedness messages has proven to be a very effective platform,” the guide continues. “We continue to reach and engage a wide variety of audiences on all hazards preparedness via ‘zombie preparedness.’”

If, as the interpreters of Nostradamus’ Yearly-Horoscope believe, a zombie invasion is nigh, then it will be a great told-you-so moment for the CDC. 

The CDC's "Zombie Preparedness" guide has quite the graphic poster.
The CDC’s “Zombie Preparedness” guide has quite the graphic poster.
CDC

“Few young people: half-dead to give a start,” the 16th century astrologer wrote, ominously adding, “Fathers and mothers dead of infinite sorrows / Women in mourning, the pestilent she−monster: / The Great One to be no more, all the world to end.” 

To prepare for that bloody, flesh-eating worst, the CDC page links to various “Zombie Preparedness Products,” including a downloadable zombie preparedness graphic novel; a printable poster of an undead-looking, leering person with very dirty fingernails; and tips for educators looking to plan zombie-related lessons. (Sample teaching tool: “The zombie apocalypse threat is imminent. The mayor’s staff has been compromised, and it is up to you to write a speech for the mayor advising the community about what actions to take. What do you tell the community to do?”)

cdc-zombie
The CDC’s zombie preparedness page has been an internet Easter egg since 2011.
CDC

The bizarre page on the otherwise dead-serious site was published in May 2011 after the CDC’s head of communications became concerned about the agency’s reach — and decided the agency’s first ever posts to Twitter and Facebook should be fun. 

“We were talking about hurricane season, which begins 1 June. I think about hurricane season, and we put out the same messages every year, and I wonder if people even see those messages,” CDC rep Dave Daigle told The Atlantic at the time. “We have a great message here about preparedness, and I don’t have to tell you that preparedness and public health are not the sexiest topics,”

The page proved so popular, it tripled traffic to the CDC’s site and crashed its server. 

Actual zombie preppers, however, were critical of the CDC’s advice, saying it fell short in a specific way.

“”That was one of the first things we got from the zombie crowd … ‘What weapons do you guys recommend?’” Daigle said. “Remember, we’re a public-health center, so we’re not going to recommend weapons … We’ll leave that to the law-enforcement folks.”

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COVID-19 Statistics | March 4, 2021 – Lost Coast Outpost

Press release from the Humboldt County Joint Information Center:

A total of 3,246 Humboldt County residents have tested positive for COVID-19 after 16 new cases were reported today.  

The State of California has allocated Humboldt County a total of 5,010 doses of COVID-19 vaccine for next week. Of those doses, 3,510 are Pfizer, 1,300 are Moderna and 200 are Johnson & Johnson, the first single-dose COVID-19 vaccine authorized for emergency use. Humboldt County Public Health is planning to use 1,430 doses for its large-scale vaccination clinics. The remainder will be distributed to approved local vaccinators. 

Vaccination priority now includes those who work in higher education either as educators or support staff. Appointments for vaccination are invitation only, and those invitations are intended only for the recipient. Humboldt County residents who meet state qualifications for vaccination include:

  • People age 70 and over
  • Health care workers
  • Emergency services personnel
  • K-12 and early childhood education workers, including educators and support staff
  • Licensed child care providers
  • Higher education. 

Residents who are not already part of a qualifying workforce can sign up to be notified when a vaccination appointment is available for their age group by filling out the COVID-19 Vaccine Interest Form. 

To complete the Interest Form in English, visit humboldtgov.org/InterestForm.

Para completar el formulario de interés de vacunas en español, visite humboldtgov.org/formulariadeinteres

For the most recent COVID-19 information, visit cdc.gov or cdph.ca.gov. Local information is available at humboldtgov.org or during business hours by contacting covidinfo@co.humboldt.ca.us or calling 707-441-5000.
 

Local COVID-19 vaccine information: humboldtgov.org/VaccineInfo
Humboldt County COVID-19 Data Dashboard: humboldtgov.org/Dashboard
Follow us on Facebook: @HumCoCOVID19
Instagram: @HumCoCOVID19
Twitter: @HumCoCOVID19
Humboldt Health Alert: humboldtgov.org/HumboldtHealthAlert 

###

= historic data. All data from the Humboldt County Joint Information Center.

Data from CalREDIE. Zip codes not listed have experienced five cases or fewer. Zip code populations from the American Community Survey, 2018.

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Ivermectin Does Not Alleviate Mild Covid-19 Symptoms, Study Finds – The New York Times

Ivermectin, a controversial anti-parasitic drug that has been touted as a potential Covid-19 treatment, does not speed recovery in people with mild cases of the disease, according to a randomized controlled trial published on Thursday in the journal JAMA.

Ivermectin is typically used to treat parasitic worms in both people and animals, but scientific evidence for its efficacy against the coronavirus is thin. Some studies have indicated that the drug can prevent several different viruses from replicating in cells. And last year, researchers in Australia found that high doses of ivermectin suppressed SARS-CoV-2, the virus that causes Covid-19, in cell cultures.

Such findings had spurred use of the drug against Covid-19, especially in Latin America.

“Ivermectin is currently being used widely,” said Dr. Eduardo López-Medina, a doctor and researcher at the Center for Pediatric Infectious Diseases in Cali, Colombia, who led the new trial. “In many countries in the Americas and other parts of the world, it’s part of the national guidelines of treating Covid.”

But the drug has also proved divisive. While some scientists see potential, others suspect that effectively inhibiting the coronavirus may require extremely high, potentially unsafe doses. Health officials have also worried that people desperate for coronavirus treatments might take versions of the drug that have been formulated for pets. (It is commonly used to prevent heartworm in dogs.)

“There’s been a lot of conflicting views on this, sometimes extreme conflicting views,” said Dr. Carlos Chaccour, a researcher at the Barcelona Institute for Global Health who was not involved in the new study. “I think it has become another hydroxychloroquine.”

But neither the proponents nor the critics have had much rigorous data to support their views. There are few well-controlled trials of the drug’s effectiveness against Covid-19, although more are expected in the coming months. And treatment guidelines from the National Institutes of Health note that there is not enough evidence “to recommend either for or against” using the drug in Covid-19 patients.

In the new study, Dr. López-Medina and his colleagues randomly assigned more than 400 people who had recently developed mild Covid-19 symptoms to receive a five-day course of either ivermectin or a placebo. They found that Covid-19 symptoms lasted about 10 days, on average, among people who received the drug, compared with 12 days among those who received the placebo, a statistically insignificant difference.

The new trial adds much-needed clinical data to the debate over using the drug to treat Covid-19, said Dr. Regina Rabinovich, a global health researcher at Harvard’s T.H. Chan School of Public Health, who was not involved in the study.

But she noted that the trial was relatively small and did not answer the most pressing clinical question, whether ivermectin can prevent severe disease or death. “Duration of symptoms may not be the most important either clinical or public health parameter to look at,” she said.

The researchers did find that seven patients in the placebo group deteriorated after enrolling in the trial, compared to four in the ivermectin group, but the numbers were too small to draw a meaningful conclusion.

“There was a small signal there, and it would be interesting to see if that signal that we saw is real or not,” said Dr. López-Medina. “But that would have to be answered in a larger trial.”

Dr. López-Medina also pointed out that the study population was relatively young and healthy, with an average age of 37 and few of the underlying conditions that can make Covid-19 more dangerous.

Bigger trials, which are currently underway, could provide more definitive answers, said Dr. Rabinovich, who noted that she was “totally neutral” on ivermectin’s potential usefulness. “I just want data because there’s such chaos in the field.”

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Episodes 7-8 – Cells at Work!! Season 2 – Anime News Network

Disclaimer: The views and opinions in these reviews are observations made by the reviewer(s) and should in no way be construed as medical advice! If you have a question, please contact your general practitioner for information!

The fight against invading bacteria in the gut and the Immunity Trio’s face off against the Cancer Cell continues in what I’ll forever refer to as the “Yogurt Arc.” NK, Memory T, and White Blood Cell have more difficulty than usual thanks to Regulatory T Cell. RT Cell has appeared in previous episodes, but she’s usually relegated to ‘office work’ with Helper T Cell. These final episodes show that she’s equally capable of combat…against the other immune cells.

Visually, it can seem ridiculous that any cell could look at Cancer Cell and think “Yeah, this is normal;” in fact I think the plot structure would benefit if there was some kind of physical representation as to why RT Cell can’t ‘see’ that Cancer Cell is for the overall body. Regardless, RT prevents Memory T from being able to effectively attack the Cancer Cell because she sees it as part of the host’s body and her job is to prevent immune cells from attacking and killing healthy cells within the body. Think back to Cells at Work! Code Black where the Killer T Cells went nuts and caused havoc in the scalp; that’s a perfect example of when a Regulatory T Cell should have stepped in. Now I’m interested to know why that doesn’t happen. Anyway, Regulatory T Cell’s interference is unfortunately part of the reason cancer cells can grow in the human body undetected until other problems arise and why medical procedures to treat cancer are so extreme.

Meanwhile, in the gut, all those lactic bacteria storm in and make short work of the invading bacteria. The opportunistic bacteria switch sides in favor of the good guys so they can go on freeloading in the gut. I’ll be honest, the knowledge that my guts are basically a biosphere for bacteria to just hang out with little to no real symbiotic relationship pisses me off. If you’re going to enjoy all the delicious food I eat, couldn’t you at least, I don’t know, give me a superpower or something? Anyway, with the bad bacteria wiped out, the environment in the gut starts to resolve and is no longer a hazard to the little platelets.

The only remaining issue is Cancer Cell and he’s gone full Sephiroth in his quest of body domination. His evil plot is to initiate death in the name of cellular freedom, allowing cells to exist without the confines of their respective roles. Of course the entire body would breakdown but he sees the sacrifice as liberating. Things are looking in his favor until Memory T Cell gets his power-up-inducing flashback and releases perforin. RT Cell (hilariously) dodges and the protein-powered punch damages Cancer Cell enough to cause RT Cell to finally notice he’s not a healthy cell. The intestinal toxin clean-up strips him of his power allowing White Blood Cell to deliver the killing blow.

All in all this was actually a pretty satisfying finale battle with some semi-decent action segments for what has otherwise been a questionable production. I never got fully on board with David Production‘s cell-shading approach here and some of the episodes were less engaging than the previous season. The factoids were a little more “Biology Basics” and spending approximately half of an already very short season focusing on lactic bacteria was pretty disappointing. The return of Cancer Cell was a good send off but combining it with the journey through the gut felt forced. I’d rather have seen something related to carcinogens.

Overall I’d say the series is an adequate follow-up to the first season but it lacked the memorable gags and diversity that kept me hooked in the first season.

Rating:




Cells at Work! is currently streaming on
Funimation.

Episodes 1-2
Episode 3
Episode 4
Episode 5
Episode 6
Episodes 7-8